Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload
نویسندگان
چکیده
منابع مشابه
Cardiovascular T2-star (T2*) magnetic resonance for the early diagnosis of myocardial iron overload.
AIMS To develop and validate a non-invasive method for measuring myocardial iron in order to allow diagnosis and treatment before overt cardiomyopathy and failure develops. METHODS AND RESULTS We have developed a new magnetic resonance T2-star (T2*) technique for the measurement of tissue iron, with validation to chemical estimation of iron in patients undergoing liver biopsy. To assess the c...
متن کاملT2-star (T2*) magnetic resonance imaging for assessment of kidney iron overload in thalassemic patients.
BACKGROUND Improved survival in thalassemic patients has lead to the manifestation of morbidities such as renal dysfunction. This involvement suggests the need for a reliable and non-invasive method to assess the degree of kidney iron overload. We conducted the present study to evaluate the relationship between serum ferritin levels, liver, heart, and kidney MRI gradient echo (T2*) relaxation t...
متن کاملOn T2* magnetic resonance and cardiac iron.
BACKGROUND Measurement of myocardial iron is key to the clinical management of patients at risk of siderotic cardiomyopathy. The cardiovascular magnetic resonance relaxation parameter R2* (assessed clinically via its reciprocal, T2*) measured in the ventricular septum is used to assess cardiac iron, but iron calibration and distribution data in humans are limited. METHODS AND RESULTS Twelve h...
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As a clinician, it is important to never underestimate the power of basic science to deliver new answers to old questions. At the outset of the development of magnetic resonance (MR), scientists demonstrated differences in magnetic relaxation between normal and malignant tissues that were of significant interest, although only clinically exploited later through MR spectroscopy. Some 30 years on...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2001
ISSN: 0195-668X
DOI: 10.1053/euhj.2001.2822